Infrared Irradiation-Assisted Multicomponent Synthesis of 2-Amino-3-cyano-4H-pyran Derivatives

Authors

  • Arturo Sánchez Escuela Nacional de Ciencias Biológicas-IPN
  • Fernando Hernández Universidad de Guanajuato
  • Paulo César Cruz Escuela Nacional de Ciencias Biológicas-IPN
  • Yolanda Alcaraz Universidad de Guanajuato
  • Joaquín Tamariz Escuela Nacional de Ciencias Biológicas-IPN
  • Francisco Delgado Escuela Nacional de Ciencias Biológicas-IPN
  • Miguel A. Vázquez Universidad de Guanajuato

DOI:

https://doi.org/10.29356/jmcs.v56i2.308

Keywords:

Infrared Irradiation, three-component reaction, MCR, 4H-pyrans

Abstract

A simple, versatile, and efficient synthesis of 4H-pyran derivative compounds is achieved via a three-component cyclocondensation of aldehydes, malononitrile, and ethyl acetoacetate, using ammonium hydroxide as the catalyst, promoted by infrared irradiation. The present method offers several advantages, such as high yields, non hazardous reaction conditions as well as short reaction times.

Downloads

Download data is not yet available.

Author Biographies

Arturo Sánchez, Escuela Nacional de Ciencias Biológicas-IPN

Departamento de Química Orgánica

Fernando Hernández, Universidad de Guanajuato

Departamento de Química

Paulo César Cruz, Escuela Nacional de Ciencias Biológicas-IPN

Departamento de Química Orgánica

Yolanda Alcaraz, Universidad de Guanajuato

Departamento de Farmacia

Joaquín Tamariz, Escuela Nacional de Ciencias Biológicas-IPN

Departamento de Química Orgánica

Francisco Delgado, Escuela Nacional de Ciencias Biológicas-IPN

Departamento de Química Orgánica

Miguel A. Vázquez, Universidad de Guanajuato

Departamento de Química

Downloads

Published

2017-10-12

Issue

Vol. 56 No. 2 (2012): Regular Issue

Section

Regular Articles

License

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.