Chemical Constituents of Psacalium sinuatum
DOI:
https://doi.org/10.29356/jmcs.v53i4.975Keywords:
Psacalium, Asteraceae, Senecioneae, Tussilagininae, Modified Eremophilanes, Anti-inflammatory ActivityAbstract
A chemical study of Psacalium sinuatum afforded the furanoeremophilane decompostine, the modified eremophilanes: cacalol, cacalol acetate, dehydrocacalol, maturinin, cacalohastin, dehydrocacalohastin, adenostin B, cacalone-epi-cacalone mixture, dimaturin, adenostylide, radulifolin F, and epi-radulifolin F, in addition to hyperin, sucrose and a mixture of sitosterol-stigmasterol. Extracts and isolated compounds were tested for anti-inflammmatory activity. The hexanic extract of root showed a dose dependent activity (IC50 0.20 mg/ear).
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References
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3. Correa, J.; Romo, J. Tetrahedron 1966, 22, 685-691.
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5. Inman, W. D.; Luo, J.; Joload, S. D.; King, S. R.; Cooper, R. J. J. Nat. Prod. 1999, 62, 1088-1092.
6. Garduño-Ramírez, M. L.; Delgado, G. Rev. Soc. Quím. Méx. 2003, 47, 160-166.
7. Pérez-Castorena, A. L.; Arciniegas, A.; Villaseñor, J. L.; Romo de Vivar, A. Rev. Soc. Quím. Mex. 2004, 48, 21-23.
8. Burgueño-Tapia, E.; Hernández-Carlos, B.; Joseph-Nathan, P. J. Mol. Struct. 2006, 825, 115-123.
9. Pérez-Castorena, A. L.; Castro, A.; Romo de Vivar, A. Phytochemistry 1997, 46, 1297-1299.
10. Contreras, C.; Román, R.; Pérez, C.; Alarcón, F.; Zavala, M.; Pérez, S. Chem. Pharm. Bull. 2005, 53, 1408-1410.
11. Alarcón-Aguilar, F. L.; Jiménez-Estrada, M.; Reyes-Chilpa, R.; González-Paredes, B.; Contreras-Weber, C. C.; Román-Ramos, R. J. Ethnopharmacol. 2000, 69, 207-215.
12. Garduño-Ramírez, M. L.; Trejo, A.; Navarro, V.; Bye, R.; Linares, E.; Delgado, G. J. Nat. Prod. 2001, 64, 432-435.
13. Jiménez-Estrada, M.; Reyes Chilpa, R.; Ramírez Apan, T.; Lledias, F.; Hansberg, W.; Arrieta, D.; Alarcón Aguilar, F. J. J. Ethnopharmacol. 2006, 105, 34-38.
14. Acevedo-Quiroz, N.; Domínguez-Villegas, V.; Garduño-Ramírez, M. L. Nat. Prod. Comm. 2008, 3, 313-317.
15. Kedrowski, B. L.; Hoppe, R.W. J. Org. Chem. 2008, 73, 5177- 5179.
16. Bohlmann, F.; Zdero, C. Phytochemistry 1978, 17, 1135-1153.
17. Kakisawa, H.; Inouye, I. Tetrahedron Lett. 1969, 24, 1929-1932.
18. Hayashi, K.; Nakamura, H.; Mitsuhashi, H.; Phytochemistry 1973, 12, 2931-2933.
19. Kuroyanagi, M.; Naito, H.; Noro, T.; Ueno, A.; Fukushima, S. Chem. Pharm. Bull. 1985, 33, 4792-4797.
20. Markham, K. R.; Ternai, B.; Stanley, R.; Geiger, H.; Mabry, T. J. Tetrahedron 1978, 34, 1389-1397.
21. Rizk, A. M. Planta Med. 1979, 36, 189-190
22. Pérez-Castorena, A. L, Arciniegas, A.; Ramírez-Apan, M. T.; Villaseñor J. L.; Romo de Vivar, A. Planta Med. 2002, 68, 645-647.
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2019-06-19
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