Synthesis of Dialkyl 2-(4-oxopyridin-1(4H)-yl)dicarboxylates Through the Reaction of 4-hydroxypyridine and Dialkyl Acetylenedicarboxylate in the Presence of Triphenylphosphine

Authors

  • Bita Mohtat Karaj Branch, Islamic Azad University
  • Zohre Najafi Azar Karaj Branch, Islamic Azad University
  • Semiramis Nahavandian Karaj Branch, Islamic Azad University
  • Hoorieh Djahaniani East Tehran Branch, Islamic Azad University
  • Abbas Ahmadi Karaj Branch, Islamic Azad University

DOI:

https://doi.org/10.29356/jmcs.v55i3.827

Keywords:

4-Hydroxypyridine, dialkyl acetylenedicarboxylates, triphenylphosphine, dialkyl 2-(4-oxopyridin-1(4H)-yl)but-2-enedioates.

Abstract

4-Hydroxypyridine undergoes a smooth reaction with dialkyl
acetylenedicarboxylates in the presence of triphenylphosphine (15
mol %) to produce the E/Z isomers of dialkyl 2-(4-oxopyridin-1(4H)-yl)but-2-enedioates in high yields.

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Author Biographies

Bita Mohtat, Karaj Branch, Islamic Azad University

Department of Chemistry

Zohre Najafi Azar, Karaj Branch, Islamic Azad University

Department of Chemistry

Semiramis Nahavandian, Karaj Branch, Islamic Azad University

Department of Chemistry

Hoorieh Djahaniani, East Tehran Branch, Islamic Azad University

Department of Chemistry

Abbas Ahmadi, Karaj Branch, Islamic Azad University

Department of Chemistry

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Published

2019-03-25

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