One-Pot Regioselective Synthesis of 4-Bromopyrazole Derivatives Under Solvent Free Conditions
DOI:
https://doi.org/10.29356/jmcs.v55i4.806Keywords:
4-bromopyrazole, solvent free, N-bromosaccharin, 1, 3- diketone, arylhydrazine.Abstract
An efficient protocol for the one pot regioselective synthesis of 4-bromopyrazole derivatives from 1,3-diketones, arylhydrazines and N-bromosaccharin, in the presence of silica gel supported sulfuric acid as heterogeneous catalyst, under solvent free conditions, is reported.
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