Antibacterial Activity of Pipemidic Acid ions-MgFeAl Layered Double Hydroxide Hybrid Against E. coli and S. typhi


  • Alejandra Santana-Cruz Universidad Autónoma Metropolitana-Azcapotzalco
  • Jorge Luis Flores-Moreno Universidad Autónoma Metropolitana-Azcapotzalco
  • Roberto Guerra-González Universidad Michoacana de San Nicolás de Hidalgo
  • María de Jesús Martínez-Ortiz Instituto Politécnico Nacional



An anion exchange process was used to prepare pipemidic acid-MgFeAl composite from MgFeAl-Cl layered double hydroxide as inorganic matrix. The obtained hybrid material contains pipemidic acid anions as well as, in a less extent; carbonate and chloride species in its interlayer space. The antibacterial properties were evaluated against E. coli and S. typhi strains through dilution broth method. MgFeAl-Cl matrix resulted to be completely inactive against two bac-teria, while MgFeAl-PIP composite killed all colonies of E. coli after 90 min of exposure and showed a good activity to kill S. typhi bacteria at times as short as 120 min.


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Author Biographies

Alejandra Santana-Cruz, Universidad Autónoma Metropolitana-Azcapotzalco

Departamento de Ciencias Básicas

Jorge Luis Flores-Moreno, Universidad Autónoma Metropolitana-Azcapotzalco

Departamento de Ciencias Básicas

Roberto Guerra-González, Universidad Michoacana de San Nicolás de Hidalgo

Facultad de Ingeniería Química

María de Jesús Martínez-Ortiz, Instituto Politécnico Nacional

Escuela Superior de Ingeniería Química e Industrias Extractivas


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