Characterization and Bioactivity of Essential Oils Extracted from Cleome Brachycarpa Plant
DOI:
https://doi.org/10.29356/jmcs.v69i2.2272Keywords:
Cleome brachcarpa, antibacterial, antifungal, essential oil, anti-microbial activitiesAbstract
Abstract. Exploration of new bioactive compounds is a need of the day to meet the medicinal requirements of the world. The present study deals with the identification and assessment of phytochemical, antibacterial, and antifungal activities of the constituents present in the essential oil, water, n-hexane, and ethyl acetate extract of Cleome brachycarpa. The plant was collected from four different locations within Pakistan. The major constituents that have been identified were D-limonene, β-linalool, p-menth-1-en-8-ol, bergamiol, γ-eudesmol, viridiflorol, a-caryophyllene, of elemol, and globuol. Among these γ-eudesmol known as an anticancer agent, was in high contents that in fact highlights the medicinal importance of this plant. The biological study against gram-negative (E. coli, K. pneumoniae, S. typhimurium, P. aeruginosa, E. carotovora, A. tumefaciens), gram-positive (B. subtilis, B. atrophaeus, S. aureus) bacterial species and one fungal (C. albicans) strain revealed a significant bioactivity of the extract in inhibiting the bacterial and fungal growth.
Resumen. La exploración de nuevos compuestos bioactivos es una necesidad actual para satisfacer las necesidades medicinales mundiales. El presente estudio aborda la identificación y evaluación de las actividades fitoquímicas, antibacterianas y antifúngicas de los constituyentes presentes en el aceite esencial y el extracto de agua, n-hexano y acetato de etilo de Cleome brachycarpa. La planta se recolectó en cuatro lugares diferentes de Pakistán. Los principales constituyentes identificados fueron D-limoneno, β-linalool, p-menth-1-en-8-ol, bergamiol, γ-eudesmol, viridiflorol, α-cariofileno, elemol y globuol. Entre estos, el γ-eudesmol, conocido como agente anticancerígeno, se encontraba en altos contenidos que, de hecho, resaltan la importancia medicinal de esta planta. El estudio biológico frente a especies bacterianas gram-negativas (E. coli, K. pneumoniae, S. typhimurium, P. aeruginosa, E. carotovora, A. tumefaciens), gram-positivas (B. subtilis, B. atrophaeus, S. aureus) y una cepa fúngica (C. albicans) reveló una bioactividad significativa del extracto en la inhibición del crecimiento bacteriano y fúngico.
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