Synthesis and NMR characterization of Bile Acid Derivatives Bearing Ugi 4CR-Modified Side Chains
DOI:
https://doi.org/10.29356/jmcs.v68i2.2061Keywords:
Bile acids, Ugi 4CR, 1H NMR, 13C{1H} NMRAbstract
Abstract. The application of the four-component Ugi reaction for the synthesis of five bile acid derivatives bearing modified side chains is described. The unambiguous structural characterization and assignment of the functional 1H NMR signals and all 13C{1H} NMR chemical shifts are presented.
Resumen. Se describe la aplicación de la reacción de cuatro componentes de Ugi a la síntesis de cinco derivados de ácidos biliares que portan cadenas laterales modificadas. Se presenta la caracterización estructural inequívoca y la asignación de las señales funcionales de 1H RMN y de todos los desplazamientos químicos de 13C{1H} RMN.
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