Synthesis, Structural Analysis and Antimicrobial Screening of Mn(II) Complexes of Schiff Bases

Authors

  • V. Gomathi Seethalakshmi Ramaswami College
  • R. Selvameena Seethalakshmi Ramaswami College

DOI:

https://doi.org/10.29356/jmcs.v66i1.1621

Keywords:

Schiff bases, Mn (II) complex, antibacterial, antifungal

Abstract

Abstract. Mn(II) complexes of Schiff bases 4-((3-ethoxy-2-hydroxybenzylidene)amino)-N-(pyridin-2-yl)benzenesulfonamide (HL2) and 4-((3-ethoxy-2-hydroxybenzylidene)amino)-N-(pyrimidin-2- yl)benzenesulfonamide (HL3) were synthesized. The Schiff bases HL2 and HL3 and their complexes were characterized by analytical, conductance, magnetic susceptibility measurements, infrared, ultraviolet-visible, thermal analysis, and EI mass techniques. The spectral data of the complexes have revealed the bidentate complexing nature of the Schiff base ligand through phenoxide ion and azomethine nitrogen atoms. The antibacterial activities of complexes were tested against gram-positive bacterial species Pseudomonas aeruginosa (NCIM 2036) and fungal species Aspergillus niger (NCIM 105) and Mucor sp.  (NCIM 108) by disc diffusion method.

Keywords: Schiff bases; Mn(II) complex; antibacterial; antifungal.

 

Resumen. Los complejos de Mn(II) de las bases de Schiff 4-((3-etoxi-2-hidroxibencilideno)amino)-N-(piridin-2-il)bencenosulfonamida (HL2) y 4-((3-etoxi-2-hidroxibencilideno)amino)-N-(pirimidin-2- il)bencenosulfonamida (HL3) fueron sintetizados. Las bases de Schiff HL2 and HL3 y sus complejos fueron caracterizados por métodos analíticos, conductancia, susceptibilidad magnética, espectroscopia infrarroja y UV-vis, termogravimetría, y espectrometría de masas por impacto enectrónico. Los datos espectroscópicos obtenidos para los complejos corroboraron la coordinación bidentada de los ligantes de base de Schiff a través del ion fenóxido y el átomo de nitrógeno del grupo azometino. La actividad antibacterial de los complejos se evaluó contra cepas bacterianas gram-positivas Pseudomonas aeruginosa (NCIM 2036) y contra especies fúngicas Aspergillus niger (NCIM 105) y Mucor sp.  (NCIM 108) utilizando el método de difusión en disco.

Author Biographies

V. Gomathi, Seethalakshmi Ramaswami College

PG and Research Department of Chemistry.

R. Selvameena, Seethalakshmi Ramaswami College

PG and Research Department of Chemistry.

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Published

2021-12-27

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Regular Articles