N-Bromosuccinimide Catalyzed Three Component One-Pot Efficient Synthesis of 2,4,5-Triaryl-1H-imidazoles from Aldehyde, Ammonium Acetate, and 1,2-Diketone or α-Hydroxyketone

Authors

  • Behrooz Maleki Hakim Sabzevari University
  • Samaneh Sedigh Ashrafi Hakim Sabzevari University

DOI:

https://doi.org/10.29356/jmcs.v58i1.159

Keywords:

2, 4, 5-Triaryl-1H-imidazoles, aldehydes, ammonium acetate, 1, 2-diketone, α-hydroxyketone, N-bromosuccinimide

Abstract

A simple, green, and efficient method for the synthesis of 2,4,5-triaryl-1H-imidazoles using N-bromosuccinimide (NBS) as a catalyst under solvent-free condition is described. The major advantages of the present method are: high yields, less reaction times, solvent-free conditions, easy purification of the products, environmental friendliness, and convenient operation.

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Author Biographies

Behrooz Maleki, Hakim Sabzevari University

Department of Chemistry

Samaneh Sedigh Ashrafi, Hakim Sabzevari University

Department of Chemistry

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Published

2017-10-12

Issue

Section

Regular Articles