Convenient Reductive Amination of Aldehydes by NaBH4/Cation Exchange Resin

Authors

  • Davood Setamdideh Islamic Azad University
  • Farhad Sepehraddin Islamic Azad University

DOI:

https://doi.org/10.29356/jmcs.v58i1.152

Keywords:

NaBH4, DOWEX(R)50WX8, Reductive amination, Carbonyl compounds

Abstract

Different secondary amines have been synthesized by reductive amination a variety of aldehydes and anilines with NaBH4/DOWEX(R)50WX8 as reducing system in THF at room temperature in high to excellent yields of products (85-93%).

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Author Biographies

Davood Setamdideh, Islamic Azad University

Department of Chemistry, College of Sciences, Mahabad Branch

Farhad Sepehraddin, Islamic Azad University

Department of Chemistry, College of Sciences, Mahabad Branch

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Published

2017-10-12

Issue

Section

Regular Articles