Convenient Reductive Amination of Aldehydes by NaBH4/Cation Exchange Resin
DOI:
https://doi.org/10.29356/jmcs.v58i1.152Keywords:
NaBH4, DOWEX(R)50WX8, Reductive amination, Carbonyl compoundsAbstract
Different secondary amines have been synthesized by reductive amination a variety of aldehydes and anilines with NaBH4/DOWEX(R)50WX8 as reducing system in THF at room temperature in high to excellent yields of products (85-93%).Downloads
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