Chrysophanol, an Antimicrobial Anthraquinone from the Root Extract of Colubrina greggii
DOI:
https://doi.org/10.29356/jmcs.v50i2.1306Keywords:
Colubrina greggii, Rhamnaceae, chrysophanol, antimicrobial activity, antraquinoneAbstract
Abstract. The methanolic extract of the root of Colubrina greggii S. Watson showed antimicrobial activity against Bacillus subtilis and
Staphylococcus aureus. The bioassay-guided purification of the organic crude extract resulted in the isolation and identification of
chrysophanol (1,8-dihydroxy-3-methylanthracenedione), as the metabolite responsible for the antimicrobial activity.
Resumen. El extracto metanólico de las raíces de Colubrina greggii S. Watson mostró actividad antibacteriana contra Bacillus subtilis y Staphylococcus aureus. La purificación biodirigida del extracto orgánico crudo de las raíces permitió el aislamiento y la identificación de crisofanol (1,8-dihydroxy-3-methylanthracenediona) como el metabolito responsable de la actividad antimicrobiana.
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