Evaluation of the Role of Matrix Matching for LA-ICP-MS Calibration Approaches in Quantitative Elemental Analysis of Tooth Enamel

Barbara Wagner, Olga Syta, Luiza Kępa, Ewa Bulska, Irena Segal, Ludwik Halicz


A mineral apatite –based calibration approach for Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) was proposed in this work to be used for quantitative multielemental analysis of tooth enamel samples. Tooth enamel is composed mainly of hydroxyapatite therefore natural apatite crystals were expected to fit the matrix. Mineral samples were partially digested and quantitatively analyzed in respect of their bulk, elemental composition by means of ICP-MS/OES. The obtained quantitative data were used to construct the LA-ICP-MS calibration curves based on the apatite crystals for the selected 32 elements. The correlation coefficient values were calculated for each element and varied from none correlation for the most heterogeneous element (Al) to the value above 0.99 (U, REE, etc.), while calibration curve based on 3 selected mineral samples was applied. The usefulness of the proposed calibration approach was evaluated during investigations of elemental composition of tooth enamel and reference materials (NIST 1400, NIST 1486) leading to the promising results.


LA-ICP-MS; matrix-matching; calibration

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DOI: http://dx.doi.org/10.29356/jmcs.v62i2.410


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Journal of the Mexican Chemical Society (J. Mex. Chem. Soc.) Vol 62, No 2 (2018). Quarterly publication (April-June). Edited and distributed by Sociedad Química de México, A.C. Barranca del Muerto 26, Col. Crédito Constructor, Del. Benito Juárez, C.P. 03940, Mexico City. Phone: +5255 56626837; +5255 56626823 Contact: soquimex@sqm.org.mx http://www.sqm.org.mx Editor-in-Chief: Ignacio González-Martínez. Indexed Journal. Certificate of reserved rights for recurrent publications under digital distribution granted by the Instituto Nacional del Derecho de Autor (INDAUTOR): 04-2018-091118040000-203. Certificate of lawful title and content: Under procedure. ISSN-e granted by the Instituto Nacional del Derecho de Autor (INDAUTOR): 2594-0317. ISSN granted by the Instituto Nacional del Derecho de Autor (INDAUTOR): 1870-249X. Postal registration of printed matter deposited by editors or agents granted by SEPOMEX: IM09-0312 Copyright © Sociedad Química de México, A.C. Total or partial reproduction is prohibited without written permission of the right holder. The Figures/schemes quality and the general contents of this publication are full responsibility of the authors. Updated December 12th, 2018 by Adriana Vázquez (editorial assistant, e-mail: editor.jmcs@gmail.com), J. Mex. Chem. Soc., Sociedad Química de México, A.C.