A Green and Simple Protocol one-pot Biginelli Condensation using Dicalcium Phosphate as Reusable Catalyst

Authors

  • Zakaria Benzekri Ibn Tofaïl University
  • Redoua Benhdidou Ibn Tofaïl University
  • Sara Hamia Ibn Tofaïl University
  • Houda Serrar Ibn Tofaïl University
  • Said Boukhris Ibn Tofaïl University
  • Brahim Sallek Ibn Tofaïl University
  • Amina Hassikou Ibn Tofaïl University
  • Abdelaziz Souizi Ibn Tofaïl University

DOI:

https://doi.org/10.29356/jmcs.v61i3.347

Keywords:

Heterogeneous catalysis, Green process, Dicalcium phosphate, 3, 4-Dihydropyrimidin-2-ones, 4-Dihydropyrimidin-2-thiones

Abstract

Dicalcium phosphate dihydrate (DCPD) was used as a green and reusable catalyst in order to synthesized two important categories of heterocycles, 3,4-dihydropyrimidin-2-ones and 3,4-dihydropyrimidin-2-thiones. The advantages of our method are as follow: short reaction times, green process, reduced environmental hazards and high isolated yield of products.

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Author Biographies

Zakaria Benzekri, Ibn Tofaïl University

Laboratory of Organic Chemistry, Organometallic and Theoretical. Faculty of Sciences

Redoua Benhdidou, Ibn Tofaïl University

Laboratory of Organic Chemistry, Organometallic and Theoretical. Faculty of Sciences

Sara Hamia, Ibn Tofaïl University

Laboratory of Organic Chemistry, Organometallic and Theoretical. Faculty of Sciences

Houda Serrar, Ibn Tofaïl University

Laboratory of Organic Chemistry, Organometallic and Theoretical. Faculty of Sciences

Said Boukhris, Ibn Tofaïl University

Laboratory of Organic Chemistry, Organometallic and Theoretical. Faculty of Sciences

Brahim Sallek, Ibn Tofaïl University

Laboratory of Agricultural Resources and Process Engineering. F Faculty of Sciences

Amina Hassikou, Ibn Tofaïl University

Laboratory of Organic Chemistry, Organometallic and Theoretical. Faculty of Sciences

Abdelaziz Souizi, Ibn Tofaïl University

Laboratory of Organic Chemistry, Organometallic and Theoretical. Faculty of Sciences

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Published

2017-10-26

Issue

Vol. 61 No. 3 (2017): Regular Issue

Section

Regular Articles

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